Recently Published
Papers by Dr. Michael Fry
The
University of Washington’s Lawrence Loeb
and his Israeli counterpart, Professor Mickey
Fry, of Technion-Israel Institute of Technology
are studying the effects of the deterioration
of DNA replication, which leads to the fragile
X syndrome, a genetic disorder. Loeb says, “The
connection with Israel was vital and beneficial
to both sides.” The research team has
published more than 25 scientific papers and
co-authored a book. Dr. Michael Fry
The following papers were published by Dr. Fry’s
laboratory with the acknowledged support of Conquer
Fragile X Foundation.
1. Weisman-Shomer, P., Cohen, E. and Fry, M.
Interruption of the fragile X syndrome expanded
sequence d(CGG)n by interspersed d(AGG) trinucleotides
diminishes the formation and stability of d(CGG)n
tetrahelical structures. Nucleic Acids Res. 28:
(2000) 1535-1541
2. Uliel, L., Weisman-Shomer, P., Oren-Jazan,
H., Newcomb, T., Loeb, L.A., and Fry, M. Human
Ku antigen tightly binds and stabilizes a tetrahelical
form of the fragile X syndrome d(CGG)n expanded
sequence. J. Biol. Chem. 275: (2000) 33134-33141
3. Kamath-Loeb, A.S., Loeb, L.A., Johansson,
E., Burgers, P.M.J., and Fry, M. Interactions
between the Werner syndrome helicase and DNA polymerase
facilitate copying of tetraplex and hairpin structures
of the d(CGG)n trinucleotide repeat sequence.
J. Biol. Chem. 276: (2001) in press
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Fundraising
Golf Tournament Planned
The
Golf Tournament Fundraising Committee met recently
at The Governors Club to formulate plans for a
fall event. The effort will be headed up by Kyle
Henderson and assisting him will be Wende Banks,
Gail Henderson and Barkley Henderson. We will
be calling on many of our friends and supporters
to help us make this an outstanding event.
Reception
and Dinner for CFXF Parents and Grandparents
In
NovemberMatthew Hollin’s grandparents, Harris
and Sande Hollin, and Mr. and Mrs. William Bell
hosted a reception and dinner for CFXF families
and research supporters. It was held at the beautiful
landmark Colony Hotel on Palm Beach. There were
many comments from the guests and two of those
particularly reflect the value of the “get-together”.
“Thank
you ! We have had a great time venting and bragging
and laughing !!”
“Thank you so very much, Harris. It felt
so good to meet and share with other families
going through the same experience. It felt so
good to not have to explain.”
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